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    Home ยป Learn About Paleo & Keto Diets

    Understanding Insulin

    Last Modified: Feb 7, 2023 by Paleo Leaper ยท This post may contain affiliate links ยท Leave a Comment

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    Confused about insulin? Tired of seeing it blamed for everything from obesity to acne without knowing exactly what it is? Hereโ€™s a quick explanation in plain English.

    insulin

    A lot of people have two big misconceptions about insulin:

    • Itโ€™s an evil hormone that exists to make you fat; the lower your insulin levels, the better.
    • Carbs cause high insulin levels which drive fat gain: just eliminate carbs and your insulin levels will take care of themselves.

    Both of these statements are incomplete at best, and by the end of this article, you should understand why.

    What is Insulin?

    Insulin is a hormone produced in the pancreas. In healthy, non-diabetic, non-obese people, insulin is responsible for important things likeโ€ฆ

    • Muscle gain: as every bodybuilder knows, insulin is anabolic. It helps your body turn dietary protein into muscle.
    • Blood sugar control and energy storage: insulin controls blood sugar within a tight range. This is important: itโ€™s very dangerous to have too many simple sugars just hanging out in your bloodstream.
    • Satiety: insulin helps make you feel full after a meal. Yes, full. Not hungry. If eating refined carbs makes you ravenous, itโ€™s because of the blood sugar highs and crashes, not because your body released insulin in response.
    • Bone strength: insulin helps maintain bone mass and even stimulate new bone growth.

    Thatโ€™s how insulin works in healthy people. Many people in the US today have diabetes or some degree of impaired insulin metabolism, and for those people, insulin metabolism is very different. In diabetes, the pancreas either donโ€™t produce insulin at all (Type 1 Diabetes) or the rest of the body doesnโ€™t respond properly to the insulin they do produce (Type 2 Diabetes/metabolic syndrome). This obviously means that insulin works differently in diabetes, but diabetes is not what this particular article is about.

    So with that said, hereโ€™s a look at how insulin works, what insulin sensitivity and insulin resistance are, what they have to do with body weight, and why metabolic health doesnโ€™t necessarily mean keeping insulin as low as possible. A lot of the evidence is taken from this review and this one, both free for anyone to read.

    Insulin and Fat Storage

    Thereโ€™s a very common oversimplification that โ€œinsulin causes fat storage,โ€ but itโ€™s much more complicated than that.

    In healthy people, insulin shows up after a meal to stabilize blood sugar. Yes, as part of this stabilization, it does store some energy as fat, but hereโ€™s the thing: a healthy person then burns that stored fat for energy in between meals. Just after a meal, youโ€™re in โ€œfat-storingโ€ mode: insulin levels are high, glucose is being stored, and glucose production in the liver is turned down. But then between meals, you switch to running off that stored fuel: insulin levels are low, the stored glucose is being burned and more glucose is being produced in the liver.

    When insulin is working this way, its fat-storage function isnโ€™t โ€œbad.โ€ In fact, itโ€™s good: it gives you a steady supply of energy throughout the day, so you donโ€™t have to walk around with a nutrient drip attached to your arm all the time. And it also helps regulate appetite and let you know when your body is full. One of the major reasons why fructose may be more obesogenic than glucose is that it doesnโ€™t raise insulin as much.

    The technical name for this happy state of affairs is insulin sensitivity. In insulin-sensitive people, insulin shows up when itโ€™s needed after a meal, does its job, and then packs up and goes home without a fuss. The person changes smoothly from โ€œfat-storingโ€ to โ€œfat-burningโ€ mode throughout the day, and the net result is that their weight stays stable.

    In other words, available evidence does not show that insulin is โ€œbadโ€ or that it โ€œcauses obesity.โ€ Healthy people have insulin highs and lows throughout the day, and donโ€™t gain weight. So then what is the problem with insulin?

    When Insulin Metabolism Goes Wrong

    The opposite of insulin sensitivity is insulin resistance. In insulin resistance, your body produces insulin normally, but doesnโ€™t use it properly, and the whole delicate balance of blood sugar regulation, fat storage, and fat burning breaks down. This causes all kinds of problems, including chronically high insulin, and it can cause weight gain because โ€œfat-storingโ€ mode is always on, and โ€œfat-burningโ€ mode is always off.

    This is what most people are probably thinking of when they say things like โ€œhigh insulin levels cause weight gain,โ€ but insulin resistance is not the way insulin works in healthy people. Itโ€™s a very complicated problem, with many different causes. Just to name a few:

    • Chronically high fructose (sugar) consumption or overconsumption of simple carbohydrates in general. Panicking over fruit is counterproductive and unnecessary, but sugar-sweetened soft drinks are probably a bad idea.
    • Unhealthy gut flora. Was there ever a health problem where the gut flora werenโ€™t involved? Gut dysbiosis contributes to insulin resistance in various ways.
    • Chronic stress (including but not limited to sleep deprivation, starvation, psychological stress, and social isolation).
    • Hormone imbalances. For example, women with PCOS often have insulin resistance or metabolic syndrome.
    • Some medications, including beta-blockers, steroids, and some diuretics.
    • Obesity, especially abdominal obesity (an apple-shaped silhouette as opposed to pear-shaped).
    • All other things being equal, women also have generally better insulin sensitivity than men.

    (Also, just as a note, itโ€™s commonly repeated that eating saturated fat causes insulin resistance. This may be true in rats, but it doesnโ€™t pan out in human trials. You can read an explanation here.)

    Insulin and Carbs: Whatโ€™s the Deal?

    The list above should make it very clear that carbs are far from the only thing affecting insulin levels. In fact, theyโ€™re not even the only macronutrient that spikes insulin: protein will do it, too. The effect that carbohydrates have on your insulin levels depends on many different factors:

    • In healthy, non-insulin-resistant people, eating large amounts of refined sugar contributes to insulin resistance, especially if there
    WhitePotato Paleo
    Not pictured: the cause of the "obesity epidemic."

    are also nutrient deficiencies involved. But eating carbohydrates from whole foods (especially whole foods high in fiber) does not. Resist the urge to generalize from a 2-liter of Coke to a potato: they are completely different foods and have completely different effects.

    • In people who are already insulin resistant (if youโ€™ve been eating a lot of junk food for much of your life, this is likely to be you), eating a relatively low-carb diet can help improve insulin sensitivity, even if you arenโ€™t actively diabetic.

    Itโ€™s true that a lot of people today are already insulin resistant; those people might truly benefit from a lower-carb diet to restore insulin sensitivity. But this is a therapeutic diet for a disease state; that doesnโ€™t make it a requirement for the entire population.

    Summing it Up

    Insulin is a hormone that affects fat storage and appetite; in healthy people, it naturally rises and falls over the course of a day. Many people do have chronically elevated insulin, and that really is a problem, but it doesnโ€™t make insulin itself the bad guy. Letโ€™s go back for a minute to the two big misconceptions about insulin from the beginning:

    • Itโ€™s an evil hormone that exists to make you fat; the lower your insulin levels, the better.

    Thatโ€™s not true. Insulin exists to keep you alive and regulate energy storage. Chronically elevated insulin levels are dangerous, but fluctuations throughout the day are completely normal.

    • Carbs cause high insulin levels which drive fat gain: just eliminate carbs and your insulin levels will take care of themselves.

    Thatโ€™s not true, either. In healthy people, eating carbohydrates from whole foods does not cause unhealthy insulin levels, and maintaining insulin sensitivity doesnโ€™t have to mean eliminating carbs. Also, all kinds of other things affect insulin metabolism (sleep and exercise, for example).

    Again, this all gets a lot more complicated when you start talking about diabetes. But itโ€™s worth at least understanding how insulin works in healthy people - not everyone is a diabetic, and not everyone needs to eat like one!

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